Design, synthesis and biological evaluation of novel bergapten derivatives as potent lipid lowering agents
The aim of this study was to synthesize novel amide derivatives of bergapten and evaluate their lipid-lowering and telemarkskongen flue triglyceride-lowering activities in mice.Amide derivatives of bergapten were synthesized by using lactone ring opening strategy in DMSO using NaOH as base followed by alkylation in presence of methyl iodide.The com